January 29, 2012

UN refugee chief: economic crisis fueling conflict (AP)

DAVOS, Switzerland ? The U.N.’s refugee chief has warned leaders meeting in Switzerland this week that the global economic crisis is fueling conflicts around the world.

Antonio Guterres told The Associated Press on Friday that rising food prices and growing unemployment are hitting those already at the bottom hardest.

Guterres says existing humanitarian hotspots in Afghanistan, Iraq and Somalia aren’t going away while new emergencies are emerging in places like South Sudan.

He urged donors to increase funding to prevent aid for 500,000 people in the newly independent country from drying up.

Guterres also says that only if political solutions are found to each crisis can there be peace and security in the world.

Source: http://us.rd.yahoo.com/dailynews/rss/eurobiz/*http%3A//news.yahoo.com/s/ap/20120127/ap_on_re_eu/eu_davos_forum_humanitarian_crises

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January 28, 2012

Research: South Africans most active tweeters (AP)

JOHANNESBURG ? Young people tweeting from BlackBerrys and iPhones are driving the growth of Twitter in Africa, with South Africans by far the most vociferous, according to new research published Thursday.

Kenya-based Portland Communications and Tweetminster published findings indicating Twitter in Africa is widely used for social conversation and is fast becoming an important source of information. More than 80 percent of those polled said they mainly used it for communicating with friends, 68 percent said they use it to monitor news and 22 percent to search for jobs, the companies said.

The research analyzed more than 11.5 million geographically pinpointed tweets originating on the continent during the last three months of 2011. That was complemented by a survey of 500 of Africa’s most active tweeters.

South Africans, with the continent’s biggest economy, were the most prolific with over twice as many tweets at 5,030,226 than the next most active country of Kenya with 2,476,800 tweets. Surprisingly, Africa’s most populous nation, Nigeria, had only 1,646,212 tweets from its more than 160 million people. It was followed by Egypt with 1,214,062 and Morocco with 745,620 tweets.

African tweeters are young, averaging 20 to 29 years, compared to 39 worldwide, the report said. And some 57 percent of analyzed tweets were sent from mobile phones, mainly BlackBerrys and iPhones.

The researchers noted how few African business and political leaders were joining Africa’s burgeoning Twittersphere.

“With some notable exceptions, we found that business and political leaders were largely absent from the debates playing out on Twitter across the continent,” they said. “As Twitter lifts off in Africa, governments, businesses and development agencies can really no longer afford to stay out of a new space where dialogue will increasingly be taking place.”

Among noted Twitter users are President Paul Kagame of Rwanda and Kenya’s Prime Minister Raila Odinga. Kagame got into an infamous Twitterspat last year with journalist Ian Birrell of The Guardian of London, with the two trading tweets about human rights and repression in the central African nation. The cyber-conversation first was joined by Kagame’s foreign minister, and then went global.

While Kenyan soldiers and fighters of an extremist Somali Islamist group have been fighting each other, their spokesman have taken the battle onto Twitter, with taunts, accusations and insults being directly traded in a rare engagement on the Internet.

On Thursday, South Africa’s new Corruption Watch campaign launched, including a Twitter account where tweeters encouraged each other to make it “the No. 1 followed Twitter account in South Africa.”

The research, called “How Africa Tweets,” found Twitter is helping form new links within Africa. The majority of those surveyed said at least half of the Twitter accounts they followed were based on the continent.

Beatrice Karanja, head of Portland Nairobi, said: “We saw the pivotal role of Twitter in the events in North Africa last year, but it is clear that Africa’s Twitter revolution is really just beginning.”

Online:

Rwanda’s President Paul Kagame: http://twitter.com/paulkagame

Kenyan Prime Minister Raila Odinga: http://twitter.com/odinga_raila

Kenyan military spokesman Emmanuel Chirchir: http://twitter.com/Major_chirchir

Corruption Watch: http://twitter.com/Corruption_SA

Source: http://us.rd.yahoo.com/dailynews/rss/personaltech/*http%3A//news.yahoo.com/s/ap/20120126/ap_on_hi_te/af_how_africa_tweets

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January 28, 2012

Discovery of new vaccine approach for treatment of cancer

[ Back to EurekAlert! ] Public release date: 27-Jan-2012
[ | E-mail | Share Share ]

Contact: Caoimhe Ni Lochlainn
communications@tcd.ie
353-189-62310
Trinity College Dublin

The findings were published online in Cancer Research

Scientists in Trinity College Dublin, Ireland, have developed a new vaccine to treat cancer at the pre-clinical level. The research team led by Professor Kingston Mills, Professor of Experimental Immunology at Trinity College Dublin discovered a new approach for treating the disease based on manipulating the immune response to malignant tumours. The discovery has been patented and there are plans to develop the vaccine for clinical use for cancer patients.

The first cancer vaccine Sipuleucel-T (Provenge) was licensed last year for use in prostate cancer patients unresponsive to hormone treatment. Unfortunately, this cell based vaccine only improves patient survival by an average of 4.1 months. Vaccines for infectious diseases are highly effective at generating immune responses that prevent infection with bacteria or viruses. The immune system can also protect us against tumours and in theory a vaccine approach should be effective against cancer. In practice this has proven very difficult because unlike infectious diseases, tumours are derived from normal human cells, and not made up of foreign substances or antigens capable of triggering an immune response. The tumours instead produce molecules that suppress the efficacy of the immune system. They generate regulatory cells that inhibit the immune response that could potentially clear the tumours.

Professor Mills’ group has developed a novel vaccine and immunotherapeutic approach that can overcome these obstacles and has the potential to significantly improve on existing technologies. The therapy is based on a combination of molecules that manipulates the immune response to curb the regulatory arm while enhancing the protective arm, allowing the induction of specialist white blood cell called killer T cells to target and eliminate the tumours. The new vaccine approach was found to be highly effective at pre-clinical stage in treating a range of cancers in murine models.

The findings were published in December online in Cancer Research, the leading journal of The American Association of Cancer Research. The research was performed by a Senior Postdoctoral Fellow Dr Neil Marshall, at Trinity College Dublin, with the help of two PhD students, Anna-Maria Corcoran and Karen Galvin and was funded by a Science Foundation Ireland Principal Investigator award to Professor Mills. The discoveries have been patent protected and Professor Mills has plans to translate them to the clinic via a TCD Campus Company, TriMod Therapeutics that he co-founded with Dr Jeremy Skillington.

###

For a copy of the Cancer Research article click on: http://cancerres.aacrjournals.org/content/early/2011/12/09/0008-5472.CAN-11-0307.abstract



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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 27-Jan-2012
[ | E-mail | Share Share ]

Contact: Caoimhe Ni Lochlainn
communications@tcd.ie
353-189-62310
Trinity College Dublin

The findings were published online in Cancer Research

Scientists in Trinity College Dublin, Ireland, have developed a new vaccine to treat cancer at the pre-clinical level. The research team led by Professor Kingston Mills, Professor of Experimental Immunology at Trinity College Dublin discovered a new approach for treating the disease based on manipulating the immune response to malignant tumours. The discovery has been patented and there are plans to develop the vaccine for clinical use for cancer patients.

The first cancer vaccine Sipuleucel-T (Provenge) was licensed last year for use in prostate cancer patients unresponsive to hormone treatment. Unfortunately, this cell based vaccine only improves patient survival by an average of 4.1 months. Vaccines for infectious diseases are highly effective at generating immune responses that prevent infection with bacteria or viruses. The immune system can also protect us against tumours and in theory a vaccine approach should be effective against cancer. In practice this has proven very difficult because unlike infectious diseases, tumours are derived from normal human cells, and not made up of foreign substances or antigens capable of triggering an immune response. The tumours instead produce molecules that suppress the efficacy of the immune system. They generate regulatory cells that inhibit the immune response that could potentially clear the tumours.

Professor Mills’ group has developed a novel vaccine and immunotherapeutic approach that can overcome these obstacles and has the potential to significantly improve on existing technologies. The therapy is based on a combination of molecules that manipulates the immune response to curb the regulatory arm while enhancing the protective arm, allowing the induction of specialist white blood cell called killer T cells to target and eliminate the tumours. The new vaccine approach was found to be highly effective at pre-clinical stage in treating a range of cancers in murine models.

The findings were published in December online in Cancer Research, the leading journal of The American Association of Cancer Research. The research was performed by a Senior Postdoctoral Fellow Dr Neil Marshall, at Trinity College Dublin, with the help of two PhD students, Anna-Maria Corcoran and Karen Galvin and was funded by a Science Foundation Ireland Principal Investigator award to Professor Mills. The discoveries have been patent protected and Professor Mills has plans to translate them to the clinic via a TCD Campus Company, TriMod Therapeutics that he co-founded with Dr Jeremy Skillington.

###

For a copy of the Cancer Research article click on: http://cancerres.aacrjournals.org/content/early/2011/12/09/0008-5472.CAN-11-0307.abstract



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-01/tcd-don012712.php

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January 28, 2012

Designers of Exotic Materials Learn New Tricks from Animals (preview)

Feature Articles | More Science Cover Image: February 2012 Scientific American MagazineSee Inside

Chemist Joanna Aizenberg mines the deep sea and the forest wetlands for nature’s design secrets and uses them to fashion new materials that may change the world


Image: Photograph by Jared Leeds

In Brief

  • Who: Joanna Aizenberg
  • Vocation|Avocation: Runs a biomimetics lab
  • Where: Harvard University
  • Research Focus: Takes inspiration from nature for designing new types of materials.
  • Big Picture: ?What we do, then, is study interesting biological systems, but with the eyes of a physical scientist.?

Among the first things you notice when you step into the corner office of Harvard University professor Joanna Aizenberg are the playthings. Behind her desk sit a sand dollar, an azure butterfly mounted in a box, a plastic stand with long fibers that erupt in color when a switch is pulled, and haphazard rows of toys. Especially numerous are the Rubik?s cubes?the classic three-by-three, of course, but also ones with four, five, six and even seven mini cubes along each edge. An eight-year-old would be in heaven.



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January 27, 2012

A Bad Night for Newt (ABC News)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/192087563?client_source=feed&format=rss

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January 27, 2012

Fed says full recovery could take 3 more years (AP)

WASHINGTON ? The Federal Reserve signaled Wednesday that a full economic recovery could take nearly three more years, and it went further than ever to assure consumers and businesses that they will be able to borrow cheaply well into the future.

The central bank said it would probably not increase its benchmark interest rate until late 2014 at the earliest ? a year and a half later than it had previously said.

The new timetable showed the Fed is concerned that the recovery remains stubbornly slow. But it also thinks inflation will stay tame enough for rates to remain at record lows without igniting price increases.

Chairman Ben Bernanke cautioned that late 2014 is merely its “best guess.” The Fed can shift that plan if the economic picture changes. But he cast doubt on whether that would be necessary.

“Unless there is a substantial strengthening of the economy in the near term, it’s a pretty good guess we will be keeping rates low for some time,” he said.

The Fed has kept its key rate at a record low near zero for about three years. Its new time frame suggests the rate will stay there for roughly an additional three years.

The bank’s tepid outlook also suggests it’s prepared to do more to help the economy. One possibility is a third bond-buying program that would seek to further drive down rates on mortgages and other loans to embolden consumers and businesses to borrow and spend more.

In a statement after a two-day policy meeting, the Fed said it stands ready to adjust its “holdings as appropriate to promote a stronger economic recovery in the context of price stability.”

Treasury yields fell after the midday announcement. But yields stopped falling after the bank later issued forecasts for the economy and interest rates. They showed that while some members foresee super-low rates beyond 2014, six of the 17 members forecast a rate increase as early as this year or next.

It was the first time the Fed had released interest-rate forecasts from its committee members. It will now do so four times a year, when it also updates its economic outlook.

The rate forecasts are an effort to provide more explicit clues about the Fed’s plans. They also coincide with a broader Fed effort to make its communications with the public more open.

Lower yields on bonds tend to encourage investors to shift money into stocks, which can boost wealth and spur more spending.

Stocks, which had traded lower before the Fed’s announcement, quickly recovered their losses. The Dow Jones industrial average closed at 12,758.85, its highest close in more than eight months.

Some economists said the new late-2014 target may foreshadow further Fed action to try to invigorate the economy.

Julie Coronado, an economist at BNP Paribas, said she thought the Fed was indicating that it will step up its purchases of bonds and other assets if economic growth fails to accelerate ? even if it doesn’t slow.

That is a “very low bar indeed,” she wrote in a note to clients.

Other analysts fear that the Fed’s longer-term timetable for a rate increase could hamstring it, even though Bernanke stressed the Fed’s ability to adjust rates as it sees fit.

Dana Saporta, an economist at Credit Suisse, worried that the much-longer timetable would compromise the Fed’s credibility if it must raise rates sooner because of unexpectedly strong growth and inflation.

“It’s striking that the Fed would make an implicit commitment for almost three years,” Saporta said. “It seems like an awfully long time to make such a statement. Given that no one knows what will happen … the (Fed) may eventually regret this.”

The central bank slightly reduced its outlook for growth this year, from as much as 2.9 percent forecast in November down to 2.7 percent. For the first time, the Fed provided an official target for inflation ? 2 percent ? in a statement of its long-term policy goals.

The bank sees unemployment falling as low as 8.2 percent this year, better than its earlier forecast of 8.5 percent. December’s unemployment rate was 8.5 percent.

Those rates are still far higher than normal. The Fed didn’t set a formal target for unemployment, but it said a rate between 5.2 percent and 6 percent would be consistent with a healthy economy.

Bernanke noted that the Fed expects only moderate growth over the next year. He pointed to the persistently depressed housing market and continued tight credit for many consumers and companies.

The Fed described inflation as “subdued,” a more encouraging assessment than last month.

“This is a fairly clear-cut signal that inflation is not on their radar at this point,” Tom Porcelli, an economist at RBC Capital Markets, wrote in a research note.

The Fed’s statement was approved on a 9-1 vote. Jeffrey Lacker, president of the Richmond regional Fed bank, dissented. He objected to the new time frame for a rate increase.

The extended time frame is a shift from the Fed’s previous plan to keep the rate low at least until mid-2013.

Beyond the adjusted outlook for interest rates, Wednesday’s statement used the same language as before in describing Europe’s debt problems and the impact on the world economy.

The threat of a recession in Europe is likely to drag on the global economy. And another year of weak wage gains in the United States could force consumers to pull back on spending, which would slow growth.

But for now, the American economy is looking a little better. Companies are hiring more, the stock market is rising, factories are busy and more people are buying cars. Even the home market is showing slight gains after three dismal years.

The Fed has taken previous steps to strengthen the economy, including purchases of $2 trillion in government bonds and mortgage-backed securities to try to cut long-term rates and ease borrowing costs.

Some Fed officials have resisted further bond buying for fear it would raise the risk of high inflation. And many doubt it would help much since Treasury yields are already near historic lows.

Source: http://us.rd.yahoo.com/dailynews/rss/economy/*http%3A//news.yahoo.com/s/ap/20120125/ap_on_re_us/us_federal_reserve

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January 27, 2012

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January 26, 2012

UK refinery of Petroplus back in production (AP)

LONDON ? The British refinery owned by collapsed Swiss energy company Petroplus Holdings has resumed shipments to customers, while authorities in France are investigating possible misuse of funds by the company.

Delivery trucks were rolling Thursday from Coryton refinery near London ? which accounts for about 10 percent of Britain’s refinery output ? for the first time since the British subsidiary was placed in administration two days earlier.

In the French city of Nanterre, an official said have opened an investigation into suspected bankruptcy through misuse of funds at a French unit of Petroplus.

The probe centers on suspicions that a bank account of Petroplus-France was stripped of about euro100 million ($129 million) in funds.

Petroplus said on Wednesday that it had begun various forms of insolvency proceedings in Switzerland, France and Germany.

The company said a court had appointed Jaffe Rechtsanwaelte Insolvenzverwalter as administrator of the German operations. In France, FHB Administrateurs Judiciaires is administering the Petroplus operations.

Petroplus said it had filed in Switzerland for composition proceedings, a form of bankruptcy in which the company claims it acted in good faith.

Petroplus, Europe’s largest independent oil refiner, filed for insolvency after failing to agree with its lenders on its $1.75 billion credit line. The company reported a net loss of $413 million in the first nine months of last year.

The company had announced on Dec. 30 that it would temporarily shut down its French and Belgian refineries “given limited credit availability and the economic climate in Europe.”

Trading in the Petroplus shares had been suspended on Monday.

Refinery profitability has been squeezed as operating expenses and the cost of crude oil rose faster than the value of the products, and the economic slowdown in Europe has added to the pressure.

A survey by energy consultancy Wood Mackenzie in 2010 found that 29 of 96 refineries in the European Union did not generate a positive net cash margin.

Source: http://us.rd.yahoo.com/dailynews/rss/britain/*http%3A//news.yahoo.com/s/ap/20120126/ap_on_bi_ge/eu_britain_petroplus

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January 26, 2012

World stocks up as Apple result lifts tech shares

Dragon dance performers swing their dragon infront of the electronic board at the trading floor as part of the celebration of Chinese New Year Tuesday, Jan. 24, 2012 in Manila’s financial district of Makati, Philippines. Asian stock markets mostly rose Tuesday, shrugging off tough negotiations between Greece and its creditors amid expectations a deal to cut the country’s debt mountain will ultimately be reached. The Philippine Stock Exchange Index, however, dropped 0.74%, or 34.91 points, to close at 4,712.99. (AP Photo/Pat Roque)

Dragon dance performers swing their dragon infront of the electronic board at the trading floor as part of the celebration of Chinese New Year Tuesday, Jan. 24, 2012 in Manila’s financial district of Makati, Philippines. Asian stock markets mostly rose Tuesday, shrugging off tough negotiations between Greece and its creditors amid expectations a deal to cut the country’s debt mountain will ultimately be reached. The Philippine Stock Exchange Index, however, dropped 0.74%, or 34.91 points, to close at 4,712.99. (AP Photo/Pat Roque)

(AP) ? World stocks rose Wednesday as investors stayed calm in the face of a possible debt default by Greece to search for good deals in technology shares boosted by stunning results from Apple Inc.

Benchmark crude rose to nearly $99 per barrel while the dollar rose against the yen but fell against the euro.

European shares followed their Asian counterparts higher. Britain’s FTSE 100 rose 0.4 percent to 5,774.31. Germany’s DAX climbed 0.5 percent to 6,448.33 and France’s CAC-40 added 0.4 percent at 3,334.50.

After a session of slight losses Tuesday, Wall Street appeared headed for a higher opening. Dow Jones industrial futures rose 0.1 percent to 12,644 while S&P 500 futures added 0.2 percent to 1,314.40.

Asian stocks posted solid gains. The Nikkei 225 index in Tokyo rose 1.1 percent to close at 8,883.69. South Korea’s Kospi gained 0.1 percent to 1,952.23 and Australia’s S&P/ASX 200 added 1.1 percent to 4,271.30. Markets in Hong Kong, mainland China and Taiwan remained closed for Chinese New Year.

Japan’s powerhouse export sector got a lift from a moderation in the yen’s strength even as the country reported its first annual trade deficit since 1980. A strong yen, which hit multiple historic highs last year against the dollar, shrinks the value of overseas earnings when repatriated and makes Japanese products less competitive.

Honda Motor Corp. surged 3.8 percent. Mitsubishi Motor Corp. jumped 4.4 percent and Sony Corp. added 4.8 percent. Tire-maker Bridgestone Corp. added 4.2 percent.

Technology stocks were elevated after Apple Inc. reported earnings that sailed past analyst estimates. Apple said late Tuesday said it sold 37 million iPhones in the last three months of 2011, vastly exceeding estimates and propelling the company to record quarterly results.

That stellar performance reverberated throughout the global tech industry. South Korea’s LG Electronics Inc., which ranks No. 2 globally in flat screen televisions, jumped 4.1 percent. Hynix Semiconductor Inc., the world’s second-largest memory chip maker, added 1.9 percent.

In Australia, shares in Lynas Corp. Ltd. soared 5.1 percent after the company said it had secured the funding necessary to complete construction and start-up at its rare earths processing plant in Malaysia.

Stan Shamu of IG Markets in Melbourne said the gains in Asia suggested that investors were paying less attention to Greece, which is struggling to reach a deal with creditors to prevent a chaotic default on its massive debts. A default could trigger a financial crisis in Europe and likely beyond.

Greece is trying to get its creditors to swap Greek government bonds for new ones that have half the face value. Greece faces an important bond repayment deadline in March.

“To a large extent, traders are thinking that people are going to lose money either way in this deal, so it’s now about how we can move on,” Shamu said. Markets “are thinking more long-term. Encouraging data out of the U.S. has been good for sentiment. We also have China, which has been managing its economy very well.”

Benchmark oil for March delivery rose 8 cents to $99.03 per barrel in electronic trading on the New York Mercantile Exchange. The contract fell 63 cents to end at $98.95 per barrel on the Nymex on Tuesday.

In currency trading, the euro rose to $1.3031 from $1.3021 late Tuesday in New York. The dollar rose to 77.98 yen from 77.73 yen.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2012-01-25-World-Markets/id-2cae3cb9b75545aeab1e6b920eb06f1c

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January 26, 2012

McDonald’s 4Q net income jumps 11 pct (AP)

NEW YORK ? Budget-conscious diners continue to flock to McDonald’s, but investors are beginning to worry about the fast food giant’s higher prices and upcoming expenses.

After the company reported Tuesday that net income jumped 11 percent in the fourth quarter on Tuesday, CEO Jim Skinner said his company can perform well in any economy.

But Skinner also noted that the struggling global economy, volatile costs for ingredients and low consumer confidence present a challenge for the world’s biggest burger chain.

McDonald’s, which serves as a bellwether for the fast-food industry, has done well throughout the recession and its aftermath with a two-pronged strategy. It’s continued to attract a base of cash-strapped customers by keeping prices low, while also luring in new customers with offerings like smoothies, lattes, and remodeled restaurants.

In the fourth quarter, McDonald’s net income of $1.38 billion translated to $1.33 per share, beating the $1.29 predicted by analysts polled by FactSet. Revenue jumped 10 percent to $6.82 billion, slightly above expectations of $6.81 billion.

But the profit margin fell slightly at company-operated stores. The company blamed higher commodities costs, as well as rising costs for rent and labor in Europe, Asia, the Middle East and Africa. Its effective tax rate for the year increased to 31.3 percent from 29.3 percent, which the company indicated was partly from higher taxes in Europe.

On the news, McDonald’s shares were down 2 percent to $99.

Foreign currency exchange rates, which helped in previous quarters, did not boost this quarter’s results. Such rates were neutral during the quarter as the dollar strengthened. When the dollar is weak, revenue that McDonald’s makes overseas translates into more dollars in the U.S.

Higher costs for ingredients also continue to be an issue, even though costs for some ingredients, like wheat and corn, have leveled off. McDonald’s said it expects costs for most of its commodities in the U.S. to increase 4.5 to 5.5 percent in 2012, in line with 2011′s 4.9 percent increase. Last year, McDonald’s raised menu prices three times, for a total price increase of about 3 percent, in March, May and November.

Chief financial officer Pete Bensen said the company would continue to “strategically take increases to offset some but not all of our higher costs.”

Bensen added that McDonald’s would take “a balanced approach to growing traffic and average check” as it mulled further price increases. The company doesn’t want to raise prices too much and risk driving away customers or causing them to trade down to cheaper items.

Like many companies, McDonald’s is looking for revenue growth in emerging markets like China and Africa, where fast-growing populations present both high risk and high potential rates of return. Skinner said McDonald’s plans to open a net of 900 new restaurants in the coming year, concentrated in Asia, the Middle East and Africa, to add to the current roster of 33,500-plus locations around the world.

About 22 percent of McDonald’s revenue comes from Asia Pacific, Africa and the Middle East, up from 14 percent five years ago. That region grew revenue 13 percent over the year, faster than any other.

In the U.S., McDonald’s will focus on getting more customers into the existing 14,000-plus locations. Skinner said the approach was “not rocket science.”

“A lot of it is simple things like proper scheduling, positioning and then planning for your shift, planning for that time period from 11 (a.m.) to 1 (p.m.) for example to be able to facilitate faster service, and fast service begets more customers,” Skinner said.

Revenue in Europe, which accounts for the biggest slice of total revenue ? 40 percent ? grew by 9 percent. New items, like hamburger bagel sandwiches, helped the company maintain revenue despite the region’s “ongoing economic uncertainty.” Executives said they see room for growth in the drive-thru business and breakfast sales there.

The company said it continues to set aside money for renovating restaurants, which it sees as key to attracting new customers. Globally, McDonald’s has renovated about 45 percent of its restaurants’ interiors and 25 percent of the exteriors. But the all the remodeling has needled some franchisees who have share in the costs.

Mark Kalinowski, an analyst at Janney Capital Markets, reduced his per-share earnings estimate for this year and next on the foreign currency impact and upcoming spending. McDonald’s said it expected selling, general and administrative expenses to jump 6 percent in 2012, driven by investments in restaurants as well as spending on the London Olympics and a convention for owner-operators.

Source: http://us.rd.yahoo.com/dailynews/rss/earnings/*http%3A//news.yahoo.com/s/ap/20120124/ap_on_bi_ge/us_earns_mcdonald_s

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